PD-0009 Primary Tumor Location is a Major Independent Prognostic Factor for Mcrc Patients
نویسندگان
چکیده
منابع مشابه
Is the Location of the Tumor Another Prognostic Factor for Patients With Colon Cancer?
Purpose In this study, we investigated both the characteristics of right colon cancer (RTCC) in comparison with those of left colon cancer (LTCC) and the impact of the location of the colon cancer on the prognosis. Methods We retrospectively analyzed the cases of 974 patients with nonmetastatic colon cancer who had undergone surgery with a curative intent from January 2001 to December 2011. R...
متن کاملLeft-sided primary tumor is a favorable prognostic factor for metastatic colorectal cancer patients receiving surgery
Objective The role of surgery in metastatic colorectal cancer (mCRC) remains controversial. This study was performed to assess the impact of surgery on survival in metastatic colorectal cancer. Materials and Methods Information of mCRC patients diagnosed between January 1, 2004, and December 31, 2013, was retrieved from the Surveillance, Epidemiology, and End Results Program database. Patient...
متن کاملIs Bax/Bcl-2 Ratio Considered as a Prognostic Marker with Age and Tumor Location in Colorectal Cancer?
Background: Bax and Bcl-2 are the major members of Bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. Therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. Methods: In this study, the relative level of mRNA expression of Bax and Bcl-2 genes was deter...
متن کاملPrimary tumor inflammation in gross tumor volume as a prognostic factor for nasopharyngeal carcinoma patients
PURPOSE The objective of this study is to investigate the prognostic value of primary tumor inflammation (PTI) in nasopharyngeal carcinoma (NPC) in the era of intensity-modulated radiation therapy (IMRT). RESULTS PTI was observed in 376/1708 (22.0%) patients, and was present in the sphenoid sinus in 289/376 (76.9%), in the nasal cavity in 27 (7.2%), and in both places in 60 (15.9%). The estim...
متن کاملRE: Primary Tumor Location as a Prognostic Factor in Metastatic Colorectal Cancer.
BACKGROUND We sought to clarify the prognostic impact of primary tumor location in metastatic colorectal cancer (mCRC). METHODS We evaluated the association between tumor location and survival parameters in patients with previously untreated mCRC receiving first-line chemotherapy ± bevacizumab in three independent cohorts: a prospective pharmacogenetic study (PROVETTA) and two randomized phas...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2012
ISSN: 0923-7534
DOI: 10.1016/s0923-7534(19)66503-8